1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride - Names and Identifiers
1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride - Physico-chemical Properties
Molecular Formula | C8H9ClF3NO
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Molar Mass | 227.61 |
Melting Point | 160-170°C |
Boling Point | 231.9°C at 760 mmHg |
Flash Point | 94.1°C |
Vapor Presure | 0.0606mmHg at 25°C |
Storage Condition | Room Temprature |
1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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Hazard Class | IRRITANT |
1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride - Introduction
1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride is an organic compound with the chemical formula C8H7F3NO • HCl. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride is a white crystalline solid, soluble in water and organic solvents. It is strongly corrosive and can react with acids and alkalis.
Use:
1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride is commonly used as an intermediate in organic synthesis for the preparation of pesticides, pharmaceuticals and other organic compounds. It can be used for the synthesis of glyphosate, benzoxypiperazine and other pesticides, can also be used for the synthesis of some compounds with biological activity.
Method:
The preparation method of 1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride is more complicated. One commonly used method of preparation is the reaction of trifluoromethylbenzyl alcohol with methyl bromide to produce metrifluoromethylbenzyloxymethane. Then, meta-trifluoromethylbenzyloxymethane is reacted with aqueous ammonia to obtain the target product, meta-trifluoromethylbenzyloxyamine. Finally, meta-trifluoromethyl benzoxylamine is reacted with hydrochloric acid to form the hydrochloride salt.
Safety Information:
1-[(Ammoniooxy)Methyl]-3-(Trifluoromethyl)Benzene Chloride is a toxic compound that is irritating and corrosive. During use and operation, appropriate protective equipment should be worn to avoid contact with skin, eyes and respiratory tract. Should be used in a well-ventilated place, and pay attention to avoid contact with other chemicals and combustibles to prevent dangerous reactions. If ingested or inhaled by mistake, seek medical attention immediately.
Last Update:2024-04-09 21:00:56